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so complex that drug effects are highly difficult to determine reliably.[5] The reported development of previously clinically silent multiple sclerosis in one patient taking In the UK, it has been available since the end of July 2006. As of 2007, the drug was available in 38 countries. many experimental paradigms of neurological disease. Its main avenue of effect is reduction in appetite. Rimonabant is the first selective CB1 receptor blocker to be approved for use anywhere in the world. In Europe, it is indicated for use in conjunction with diet and exercise for the treatment of obese patients (BMI greater
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